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Risk of Rain 2 Item Tier List – Best Items in the Game in 2022

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Here is our Risk of Rain 2 Item Tier List where we have ranked all the items in the game of all rarities. Find out the best items in the game here!

In terms of being a roguelike, calling Risk of Rain 2 a masterpiece is almost criminally underselling the number of its features. The game’s simple yet extremely enjoyable roguelike gameplay loop, clear disdain for downtime, adorably minimalistic graphics fidelity, and simply superb soundtrack are only the tip of the iceberg. 

All items in Risk of Rain 2 are categorized into tiers depending on their usefulness, drop rate, effectiveness in a build, and stacking perk benefit. Each item must have a purpose, and some will wear out quickly while others will last for a long time. Furthermore, each item comes with a set of challenges to complete and accomplishing them not only unlocks the item but also earns you an achievement. Here is our Risk of Rain 2 Item Tier List.

Risk of Rain 2 Item Tier List

S Tier Items

The best items in the game are found on the S Tier. These are the items that we strongly advise you to utilize every time you play the game.

  • Will-o’-the-wisp
  • 57 Leaf Clover
  • Predatory Instincts
  • Gesture of The Drowned
  • Disposable Missile Launcher
  • Lens Makers Glasses
  • Paul’s Goat Hoof
  • ATG Missile MK 1
  • Soldier’s Syringe
  • Harvester’s Scythe
  • Tougher Times
  • Soulbound Catalyst
  • Crowbar
  • Shattering Justice

A Tier Items

This tier has several fantastic items. They just fall short in a few areas, which is the only reason they aren’t in the S tier. Regardless, these are excellent items to have on hand when playing Risk of Rain 2.

  • Royal Capacitor
  • Backup Magazine
  • Tritip Dagger
  • Fuel Cell
  • Infusion
  • Stun Grenade
  • Hopoo Feather
  • Unstable Tesla Coil
  • Berzerker’s Pauldron
  • Halcyon Seed
Risk of Rain 2 Gameplay

B Tier Items

These items are neither the most powerful nor the weakest. While they lack the necessary qualities to make the higher tiers, they do manage to stand out among the lower-tiered items on this list.

  • Bundle of Fireworks
  • Ukulele
  • Genesis Loop
  • Titanic Knurl
  • Shaped Glass
  • Kjaro’s Band
  • Ceremonial Dagger
  • Focus Crystal
  • Old Guillotine
  • Topaz Brooch
  • Jade Elephant
  • Rose Buckler
  • Runald’s Band
  • Gnarled Woodsprite
  • Shaped Glass
  • Ceremonial Dagger

C Tier Items

These items are only useful when combined with specified classes. This implies they’ll only be beneficial to you if you utilize them with the appropriate classes. They will not produce any useful results if they are used with irrelevant classes.

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  • Pearl
  • Transcendence
  • Gasoline
  • Wax Quail
  • Aegis
  • Pearl
  • Preon Accumulator
  • Beads of Fealty
  • Energy Drink
  • War Horn
  • Brilliant Behemoth
  • Queen’s Gland
  • War Banner
  • Preon Accumulator
  • Sticky Bomb
  • Armor Piercing Rounds
  • The Backup
  • Priomordial Cube
  • Fuel Array
  • Irradiant Pearl
  • Pearl
Risk of Rain 2 Gameplay

D Tier Items

The items in the D tier in Risk of Rain 2 are even less beneficial than those in the C tier. Despite their numerous shortcomings and lack of compatibility, they are nevertheless adequate for solo play or the creation of damage-dealing builds.

  • Bandolier
  • Ocular HUD
  • Old War Stealth Kit
  • Fresh Meat
  • Resonance Disc
  • Razor Wire
  • Rusted Key
  • Red Whip
  • Leeching Seed
  • Dio’s Best Friend
  • Hardlight Afterburner
  • Rusted Key
  • Brainstalks
  • Cautious Slug
  • Medkit
  • Alien Head
  • Bustling Fungus
  • Happiest Mask
  • Lepton Daisy
  • Chronobuable

F Tier Items

In Risk of Rain 2, the F tier has the very worst items. These are items that we would never suggest to anyone. As they sit in your inventory, their long cooldown times render them nearly useless.

  • Monster Tooth
  • H3AD-5T v2
  • Ghor’s Tome
  • Frost Relic
  • Blast Shower
  • The Crowdfunder
  • Milky Chrysalis
  • Little Disciple
  • Spinel Tonic
  • Brittle Crown
  • Eccentric Vase
  • Volcanic Egg
  • Radar Scanner
  • Foreign Fruit
  • Visions of Heresy
  • Helfire Tincture
  • Strides of Heresy
  • Corpsebloom
  • Effigy of Grief
  • Glowing Meteorite
  • N’Kuhanas Opinion
  • Rejuvenation Rack
  • Effigy of Grief
  • Wake of Vultures

About Risk of Rain 2

Risk of Rain 2 is a game published by Gearbox Publishing and created by Hopoo Games. The game is a third-person shooter with Roguelike elements. Both single-player and multiplayer modes are available in the game. Though the game was officially published on August 11, 2020, it was first made available for early access in 2019 on platforms such as Microsoft Windows, Nintendo Switch, PlayStation 4, and Xbox One.

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Parth Joshi

Parth is a Content Writer at MediaReferee and Editor at Gamition. He is an avid Pokemon fan and likes to make obscure Pop culture references.

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